Portal Logo
Background Image

Grow Smarter in Cali

Build your startup in a city that offers top talent, lower costs, and access to Latin American markets.

Operated by

Startups

139

Growth Rate

15.4%

Total Funding

$136.1M

Ecosystem Highlight

National Ranking

#3 in Colombia

Cali has ranked as Colombia’s 3rd-strongest startup ecosystem for six consecutive years, recognized for its exceptional startup ecosystem.

“The growth of our ecosystem is driven by the extraordinary talent of our entrepreneurs, the true protagonists of progress, and the continued support of institutions like ours, which believe in them and walk alongside them. Today, Cali is moving forward with strength and earning its place on the global map.”
Maria del Mar Palau

Maria del Mar Palau

Executive, President Cali Chamber of Commerce

Latest Opportunities & Events

Recent Startup Ecosystem News

Discover the latest startup stories and insights from the portal.

Join our Cali Ecosystem Newsletter

Our Partners

Ecosystem Stakeholders

Meet with the key players driving this vibrant startup ecosystem.

Notable Startups

Top Coworking Spaces

Notable Organizations

Want to know more about Cali startup ecosystem and its benefits?

Contact Us

Top Achievements of the Cali Startup Ecosystem

Rankings provided by

Among LATAM Cities with 2–10 Million People

#6

Cali is ranked among the top innovation ecosystems in Latin America for cities with a population between 2 and 10 million.

Global Rank Change since 2020

+53

Cali’s startup ecosystem has climbed 53 positions in the global rankings since 2020, reflecting consistent growth and increased international visibility.

Top Cybersecurity Hub in LATAM

#3

Cali ranks 3rd in Latin America for its cybersecurity startup ecosystem, showcasing strong local talent and emerging digital security ventures.

Key Benefits of Joining Cali Startup Ecosystem

Strategic Location & Competitive Advantage

As Colombia’s key Pacific Coast hub, Cali offers access to Latin American markets, high-quality bilingual talent, and lower competition than mainstream cities, ideal for both local founders and international investors looking to enter the region.

Rapidly Expanding Ecosystem

Cali’s startup scene is gaining momentum with new ventures, coworking hubs, and innovation-driven institutions. Its community is actively growing, creating momentum and visibility in the region and beyond.

Focused Sector Strengths and Cluster Development

Cali is home to well-established industry clusters, like health, agribusiness, logistics, and creative industries, making it easier for startups to plug into value chains, find early customers, and scale with sector-specific support.

Key Statistics

Foreign Investment

USD $110M

In 2024

Digital Economy Companies

800+

In Cali

Operating Data Centers

23

In 2025

Cali Ecosystem Landscape

Taxes and Incentives
  • Zonamerica is the Colombia's first free trade zone dedicated to services and technology and is located in Cali.
  • The Economic Growth Law introduced, among others, a new employment deduction according to which employers may deduct 120% of the salary payments made to employees who are under 28 years of age.
  • Bancoldex - The Colombian Business Development Bank provides compensated credit lines in Valle del Cauca, in cooperation with the Mayor's Office.
  • Fondo Emprender SENA is a seed capital fund created by the national government and assigned to the National Apprenticeship Service (SENA).
  • The Creatic Technological Development Center - aims to develop applied research projects and technology transfer, to meet the needs of the productive sector, through the implementation of innovation processes for productive and social transformation in the Colombian Southwest and the country.
Investor Landscape
  • ProColombia is Colombia’s official investment platform that brings a large amount of foreign direct investment into the region. Basing a startup in Cali will allow startups to benefit from this inflow of FDI.
  • Invest Pacific is an initiative created by the cooperation of the public and private sector to promote investment in the Cali region.
  • Valle INN Fund is an entrepreneurship program that provides advice and support to startups who are in the ideation stage of a business or that are just entering the market.
  • Several national and regional VC funds actively invest in Cali-based startups, including Progresa Capital, Fondo Emprender, Andeo, SIMMA, and Marathon Ventures.
  • Angel investing is strong via the Red Pólux network, alongside national partners like Innpulsa Colombia.
  • VCs, unicorn founders back Truora with new investment round, a startup that helps LatAm businesses onboard users via WhatsApp

Ecosystem Milestones

2025

Cali becomes the official venue of the 105th version of the Procolombia Macrorrueda, a trade promotion event.

Epic Angels, the largest investor network in Asia-Pacific, arrives in Cali, managing to mobilize more than U$ 73,000 in just two weeks for the winning startup of Capital Summit 4.0

2024
2024

NIDO and its Meetups are born as a commitment of the ecosystem to train, inspire and connect technology entrepreneurs in Cali.

The Cali Chamber of Commerce organizes the first Capital Summit, as an epicenter for investment.

2020
2016

Cali becomes home to Colombia’s first services-focused Free Trade Zone - Zonamerica.

Octopus Force is founded as a Technological Development Center officially recognized by the Ministry of Science, Technology and Innovation

2014
2008

Establishment of the Start-Upcafé as an incubator for technology-based and innovative enterprises.

Launch of the Entrepreneur Fund, administered by Colombia's National Training Service (SENA).

2002

Want to Get in Touch?

Have something to share or explore within the ecosystem? Let us know how we can help — from adding events and opportunities to discussing partnerships or ideas.
This portal and contact form are fully operated by StartupBlink, the global platform supporting ecosystem growth worldwide.

Powered By